Clinical research shows:
After just 2 psilocybin therapy sessions 71% of patients with major depression achieved lasting relief
with results maintained for 5+ years for most


I want an intake session
Check if psilocybin therapy can help me
I’d like to ask a question
once
Legal, medically supervised
psilocybin center in Europe: grounded in science,
guided by care

Most people notice changes within the first week: calmer mornings, clearer thinking,
more emotional room
“
Alexander Lebedev MD, PhD — psychiatrist, neuroscientist.
Сo-founder of ONCE20 years of therapeutic practice
100+ peer-reviewed papers in mental health, leadership roles at top European universities
When every day feels like pushing
through,decisions drain you, and your
family gets what’s left of you —
It’s not a personality weakness
It’s your brain and nervous system stuck in survival mode
Describe your state
We’d love to understand your situation, so we can help you find the best way forward.
chronic stress
I wake up tired, even after “rest”
burn out
diagnosed depression
anxiety
I feel like I’m running on 5% battery all day
simple decisions feel heavy and draining
motivation comes in flashes, then disappears for days
I can’t switch off — or I shut down completely
All clear, let’s move forward! 👉🏽
What it looks like
Step by step process that fits around your real busy life
Designed for people with full lives
No need to step away from work or family for extended periods:
only 1 day requires to be in Amsterdam
We work with people who can’t simply pause their lives. That’s why most of the program is online and easy to fit around your schedule.
Total duration is usually 4–6 weeks including: online preparation, on-site psilocybin session, and online integration psychotherapy sessions.
step 1 · 15-30 min zoom call
A free initial conversation
A calm, private conversation where you can share what’s happening and explore if this path might help.
If it feels right, we’ll schedule a medical screening — at a time that works for you.
step 2 · 60 min zoom call
Medical Screening and Personalized Plan with a licensed physician
We carefully review your medical history, medications, and well-being to ensure this experience is safe.
If appropriate, we also look at your goals and outline a personalised support plan grounded in established clinical protocols.
175 € · with vat
From here, the program is personalised to you — below is an example of what it typically looks like.
step 3 · 60 min zoom call
Two or more online Preparation Sessions with your therapist
Your therapist helps you explore any concerns, define what you want from the experience, and prepare mentally and emotionally.Mixed feelings are common. One part of you may be ready for change, while another feels cautious or unsure.
Preparation creates space for both, without forcing a decision.
We use the evidence-based Internal Family Systems (IFS) approach to:
175 € · per session
For some people, meaningful shifts already occur during preparation sessions.
Continuing further is always your choice.
step 4
Planning and Arrival in Amsterdam
We schedule a suitable date for your session. If you are traveling, we guide you through the logistics — accommodation, location of the center, what to expect on arrival.
If a visa or documents are required, we can assist you with the process.
We recommend arriving at least one day before the session.
Many choose to keep the day light — without urgent tasks or heavy decisions.
step 5 · on-site in Amsterdam
Psilocybin session (one full day)
You arrive in the morning, wearing comfortable clothes.You’re welcomed by the facilitator who will be with you throughout the session — someone you’ve already met during the preparation phase.The room feels like a peaceful living space: soft lighting, blankets, comfortable seating.We begin with a brief check-in and preparation, making sure you feel oriented and supported before starting.During the session, you may choose to lie down and close your eyes. Headphones are provided, with music selected to support focus and continuity throughout the experience.
You can open your eyes or speak at any point if you need to.Experiences can vary — sometimes calm, sometimes emotionally or psychologically intense. Your role isn’t to achieve anything in particular, but to stay present with what arises, at your own pace.The facilitator remains nearby throughout.
After the session, we take time to ensure you feel grounded and stable before leaving.
1590 € · with vat
step 6
Integration and recoveryday
We recommend to keep this day free of work and major decisions. Some people choose a short walk or time in nature; others prefer quiet rest at home or in the hotel.
Your mind and nervous system have the time and space to settle before returning to routine.
step 7 · 60 min zoom call
Two or more Integration Sessions Online
Together with your therapist, you reflect on the experience and translate insights into specific actions that support your work, relationships, and well-being.
Real change becomes practical and sustainable.
175 € · per session
once
Keizersgracht 312, 1016 EX Amsterdam, Netherlands
Clinical research shows:
After just 2 psilocybin therapy sessions71% of patients with major depression achieved lasting relief
with results maintained for 5+ years for most


I want an intake session
Check if psilocybin therapy can help me
I’d like to ask a question
once
Legal, medically supervised
psilocybin center in Europe — grounded in science, guided by care

Most people notice changes within the first week: calmer mornings, clearer thinking, more emotional room
“
Alexander Lebedev MD, PhD — psychiatrist, neuroscientist.
Сo-founder of ONCE20 years of therapeutic practice
100+ peer-reviewed papers in mental health, leadership roles at top European universities
When every day feels like pushing through, decisions drain you, and your family gets what’s left of you — It’s not a personality weakness
It’s your brain and nervous system stuck in survival mode
Describe your state
We’d love to understand your situation, so we can help you find the best way forward.
chronic stress
I wake up tired, even after “rest”
burn out
diagnosed depression
anxiety
I feel like I’m running on 5% battery all day
simple decisions feel heavy and draining
motivation comes in flashes, then disappears for days
I can’t switch off — or I shut down completely
What it looks like
Step by step process that fits around your real busy life
Designed for people with full lives
No need to step away from work or family for extended periods:
only 1 day requires to be in Amsterdam
We work with people who can’t simply pause their lives. That’s why most of the program is online and easy to fit around your schedule.
Total duration is usually 4–6 weeks including: online preparation, on-site psilocybin session, and online integration psychotherapy sessions.
step 1 · 15-30 min zoom call
A free initial conversation
A calm, private conversation where you can share what’s happening and explore if this path might help.
If it feels right, we’ll schedule a medical screening — at a time that works for you.
From here, the program is personalised to you — below is an example of what it typically looks like.
step 2 · 60 min zoom call
Medical Screening and Personalised Plan with a licensed physician
We carefully review your medical history, medications, and well-being to ensure this experience is safe.
If appropriate, we also look at your goals and outline a personalised support plan grounded in established clinical protocols.
175 € · with vat
step 3 · 60 min zoom call
Two or more online Preparation Sessions with your therapist
Your therapist helps you explore any concerns, define what you want from the experience, and prepare mentally and emotionally.Mixed feelings are common. One part of you may be ready for change, while another feels cautious or unsure.
Preparation creates space for both, without forcing a decision.
We use the evidence-based Internal Family Systems (IFS) approach to:
175 € · per session
step 4
Planning and Arrival in Amsterdam
We schedule a suitable date for your session. If you are traveling, we guide you through the logistics — accommodation, location of the center, what to expect on arrival.
If a visa or documents are required, we can assist you with the process.
We recommend arriving at least one day before the session.
Many choose to keep the day light — without urgent tasks or heavy decisions.
step 5 · on-site in Amsterdam
Psilocybin session (one full day)
You arrive in the morning, wearing comfortable clothes.You’re welcomed by the facilitator who will be with you throughout the session — someone you’ve already met during the preparation phase.The room feels like a peaceful living space: soft lighting, blankets, comfortable seating.We begin with a brief check-in and preparation, making sure you feel oriented and supported before starting.During the session, you may choose to lie down and close your eyes. Headphones are provided, with music selected to support focus and continuity throughout the experience.
You can open your eyes or speak at any point if you need to.Experiences can vary — sometimes calm, sometimes emotionally or psychologically intense. Your role isn’t to achieve anything in particular, but to stay present with what arises, at your own pace.The facilitator remains nearby throughout.
After the session, we take time to ensure you feel grounded and stable before leaving.
1590 € · with vat
step 6
Integration and recoveryday
We recommend to keep this day free of work and major decisions. Some people choose a short walk or time in nature; others prefer quiet rest at home or in the hotel.
Your mind and nervous system have the time and space to settle before returning to routine.
step 7 · 60 min zoom call
Two or more Integration Sessions Online
Together with your therapist, you reflect on the experience and translate insights into specific actions that support your work, relationships, and well-being.
Real change becomes practical and sustainable.
175 € · per session
once
Keizersgracht 312, 1016 EX Amsterdam, Netherlands